Structure information

V2 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7DW9

SPECIES

Homo sapiens

RESOLUTION

2.600

PREFERRED CHAIN

R

PUBLICATION DATE

July 21, 2021

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
vasopressin D33 1.28x28 TM1 polar (charge-charge)
vasopressin E40 1.35x35 TM1 polar (charge-assisted hydrogen bond)
vasopressin Q96 2.61x60 TM2 polar (charge-assisted hydrogen bond)
vasopressin D103 ECL1 polar (hydrogen bond with backbone)
vasopressin R104 23.49x49 ECL1 polar (charge-assisted hydrogen bond)
vasopressin K116 3.29x29 TM3 polar (charge-assisted hydrogen bond)
vasopressin M123 3.36x36 TM3 hydrophobic
vasopressin Q174 4.60x61 TM4 polar (hydrogen bond)
vasopressin W193 45.51x51 ECL2 polar (hydrogen bond)
vasopressin A194 45.52x52 ECL2 polar (hydrogen bond with backbone)
vasopressin A194 45.52x52 ECL2 polar (hydrogen bond with backbone)
vasopressin R202 5.35x36 TM5 polar (charge-assisted hydrogen bond)
vasopressin V206 5.39x40 TM5 hydrophobic
vasopressin F287 6.51x51 TM6 hydrophobic
vasopressin Q291 6.55x55 TM6 polar (hydrogen bond)
vasopressin V308 7.36x35 TM7 hydrophobic
vasopressin L312 7.40x39 TM7 polar (hydrogen bond with backbone)

Ligands

vasopressin

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

G N S L A V A V F V I S L L A L E A R A 1 G H L C L A D L A V A F L Q V L P Q L A W 2 A L I M Y S S A Y M G V M Q L Y K V A R 3 W N R P V L V A W A F S L L L S L P Q 4 Q C A A I G L T P A V F V M L A I W T V Y 5 L V I V V V Y V L C W A P F F L V Q L W 6 W P N T C S N L S A L L M L L V F P A 7
Download: PNG | SVG
ICL1 H W ICL1ECL1 R F R G ECL1ICL2 P M L A Y R H G ICL2ECL2 A Q R N V E G G S G V T D C W A C F A E P ECL2ICL3 P G G R R R G R R T G S P G E G ICL3ECL3 P E A P L E ECL3N-term M L M A S T T S A V P G H P S L P S L P S N S S Q E R P L D T R N-termC-term R T P P S L G P Q D E S C T T A S S S L A K D T S S C-term D P L L A R A E L A L L S I V F V A V A L S N G L V L A A L A R R G R R G A P I H V F I G H L C L A D L A V A L F Q V L P Q L A W K A T D P D A L C R A V K Y L Q M V G M Y A S S Y M I L A M T L D R H R A I C R S G A H W N R P V L V A W A F S L L L S L P Q L F I F W G R R T Y V T W I A L M V F V A P T L G I A A C Q V L I F R E I H A S L V P G P S E R A H V S A A V A K T V R M T L V I V V V Y V L C W A P F F L V Q L W A A W D G A P F V L L M L L A S L N S C T N P W I Y A S F S S S L R S A R G V S S E L L C C
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
V2 receptor
TM1
1x28 1.28x28 D33
1x35 1.35x35 E40
TM2
2x60 2.61x60 Q96
ECL1
23x49 23.49x49 R104
TM3
3x29 3.29x29 K116
3x36 3.36x36 M123
TM4
4x61 4.60x61 Q174
ECL2
45x51 45.51x51 W193
45x52 45.52x52 A194
TM5
5x36 5.35x36 R202
5x40 5.39x40 V206
TM6
6x51 6.51x51 F287
6x55 6.55x55 Q291
TM7
7x35 7.36x35 V308
7x39 7.40x39 L312