vasopressin (Human) [8624]



vasopressin (Human)


SMILES NC(=O)CC[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](N)CSSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)[C@H](CC(N)=O)NC1=O
InChIKey KBZOIRJILGZLEJ-LGYYRGKSSA-N
Sequence CYFQNCPRG
HELM PEPTIDE1{C.Y.F.Q.N.C.P.R.G.[am]}$PEPTIDE1,PEPTIDE1,6:R3-1:R3$$$

Chemical Properties

Hydrogen bond acceptors 16
Hydrogen bond donors 14
Rotatable bonds 19
Log P -5.404
Molecular weight (Da) 1083.4
Stereochemistry info unspecified

Database connections

Structure pdb 7BB6 7BB7 7DW9 7R0C 7KH0
Model (Boltz2) V1A V1B V2 OT
GPCRdb related ligands

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

vasopressin (Human)


Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 22
Phase III 16
Phase IV 12

Database connections

Structure pdb 7BB6 7BB7 7DW9 7R0C 7KH0
Model (Boltz2) V1A V1B V2 OT
GPCRdb related ligands

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score