Structure information

D1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7JV5

SPECIES

Homo sapiens

RESOLUTION

3.000

PREFERRED CHAIN

R

PUBLICATION DATE

Feb. 24, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
743408-71-1 D103 3.32x32 TM3 polar (charge-charge)
743408-71-1 I104 3.33x33 TM3 hydrophobic
743408-71-1 L190 ECL2 hydrophobic
743408-71-1 S198 5.42x43 TM5 polar (hydrogen bond with backbone)
743408-71-1 S198 5.42x43 TM5 polar (hydrogen bond)
743408-71-1 F288 6.51x51 TM6 aromatic (edge-to-face)
743408-71-1 F289 6.52x52 TM6 hydrophobic
743408-71-1 N292 6.55x55 TM6 polar (hydrogen bond)

Ligands

743408-71-1

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Residue Diagrams

T N G L L T S L I L L S L F C A T L I R 1 I S L A V S D L L V A L V V M P W K A V A 2 V C L N L I S A T S C M I D F A V W I N 3 A F I L I S V A W T L S V L I S F I P V 4 Y T V I M I A V P I Y F S I V S S S I A Y 5 S V I M G V F V C C W L P F F I L N C I 6 I P N L S S N A W G F W V F V D F T N 7
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ICL1 R H L R S ICL1ECL1 F W P F ECL1ICL2 P F R Y E R K M ICL2ECL2 W H K A K P T S P S D G N A T S L A E T I D N C D S S L ECL2ICL3 T T T G N G K P V E C S Q P E S S F ICL3ECL3 G S G E T Q P F C I ECL3N-term M R T L N T S A M D G T G L V V E R D F N-termC-term C Y R L C P A T N N A I E T V S I N N N G A A M F S S H H E P R G S I S K E C N L V Y L I P H A V G S S E D L K K E E A A G I A R P L E K L S P A L S V I L D Y D T D V S L E K I Q P I T Q N G Q H P T C-term S V R I L T A C F L S L L I L S T L L G N T L V C A A V I R F K V T N F F V I S L A V S D L L V A V L V M P W K A V A E I A G G S F C N I W V A F D I M C S T A S I L N L C V I S V D R Y W A I S S T P K A A F I L I S V A W T L S V L I S F I P V Q L S S R T Y A I S S S V I S F Y I P V A I M I V T Y T R I Y R I A Q K Q I R R I A A L E R A A V H A K N C Q K M S F K R E T K V L K T L S V I M G V F V C C W L P F F I L N C I L P F C D S N T F D V F V W F G W A N S S L N P I I Y A F N A D F S T F R K A L L G
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Residue Table


GPCRdb(A)
GPCRdb(A)
D1 receptor
TM3
3x32 3.32x32 D103
3x33 3.33x33 I104
TM5
5x43 5.42x43 S198
TM6
6x51 6.51x51 F288
6x52 6.52x52 F289
6x55 6.55x55 N292