Structure information

D1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7JVP

SPECIES

Homo sapiens

RESOLUTION

2.900

PREFERRED CHAIN

R

PUBLICATION DATE

Feb. 24, 2021

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
39YLC3L0ZU D103 3.32x32 TM3 polar (charge-charge)
39YLC3L0ZU I104 3.33x33 TM3 hydrophobic
39YLC3L0ZU L190 ECL2 hydrophobic
39YLC3L0ZU S198 5.42x43 TM5 polar (hydrogen bond with backbone)
39YLC3L0ZU S198 5.42x43 TM5 polar (hydrogen bond)
39YLC3L0ZU S198 5.42x43 TM5 polar (hydrogen bond)
39YLC3L0ZU S202 5.46x461 TM5 polar (hydrogen bond)
39YLC3L0ZU F288 6.51x51 TM6 aromatic (edge-to-face)
39YLC3L0ZU F289 6.52x52 TM6 hydrophobic
39YLC3L0ZU N292 6.55x55 TM6 polar (hydrogen bond)
39YLC3L0ZU F313 7.35x34 TM7 hydrophobic

Ligands

39YLC3L0ZU

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Residue Diagrams

T N G L L T S L I L L S L F C A T L I R 1 I S L A V S D L L V A L V V M P W K A V A 2 V C L N L I S A T S C M I D F A V W I N 3 A F I L I S V A W T L S V L I S F I P V 4 Y T V I M I A V P I Y F S I V S S S I A Y 5 S V I M G V F V C C W L P F F I L N C I 6 I P N L S S N A W G F W V F V D F T N 7
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ICL1 R H L R S ICL1ECL1 F W P F ECL1ICL2 P F R Y E R K M ICL2ECL2 W H K A K P T S P S D G N A T S L A E T I D N C D S S L ECL2ICL3 T T T G N G K P V E C S Q P E S S F ICL3ECL3 G S G E T Q P F C I ECL3N-term M R T L N T S A M D G T G L V V E R D F N-termC-term C Y R L C P A T N N A I E T V S I N N N G A A M F S S H H E P R G S I S K E C N L V Y L I P H A V G S S E D L K K E E A A G I A R P L E K L S P A L S V I L D Y D T D V S L E K I Q P I T Q N G Q H P T C-term S V R I L T A C F L S L L I L S T L L G N T L V C A A V I R F K V T N F F V I S L A V S D L L V A V L V M P W K A V A E I A G G S F C N I W V A F D I M C S T A S I L N L C V I S V D R Y W A I S S T P K A A F I L I S V A W T L S V L I S F I P V Q L S S R T Y A I S S S V I S F Y I P V A I M I V T Y T R I Y R I A Q K Q I R R I A A L E R A A V H A K N C Q K M S F K R E T K V L K T L S V I M G V F V C C W L P F F I L N C I L P F C D S N T F D V F V W F G W A N S S L N P I I Y A F N A D F S T F R K A L L G
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Residue Table


GPCRdb(A)
GPCRdb(A)
D1 receptor
TM3
3x32 3.32x32 D103
3x33 3.33x33 I104
TM5
5x43 5.42x43 S198
5x461 5.46x461 S202
TM6
6x51 6.51x51 F288
6x52 6.52x52 F289
6x55 6.55x55 N292
TM7
7x34 7.35x34 F313