Structure information

CT receptor

PROTEIN CLASS

Class B1 (Secretin)

PDB CODE

7TYW

SPECIES

Homo sapiens

RESOLUTION

3.000

PREFERRED CHAIN

R

PUBLICATION DATE

March 23, 2022

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Calcitonin salmon Y41 N-term hydrophobic
Calcitonin salmon W79 N-term hydrophobic
Calcitonin salmon P100 N-term hydrophobic
Calcitonin salmon D101 N-term polar (charge-assisted hydrogen bond)
Calcitonin salmon D101 N-term polar (charge-assisted hydrogen bond)
Calcitonin salmon F102 N-term hydrophobic
Calcitonin salmon W128 N-term polar (hydrogen bond)
Calcitonin salmon S129 N-term polar (hydrogen bond with backbone)
Calcitonin salmon S129 N-term polar (hydrogen bond with backbone)
Calcitonin salmon S129 N-term polar (hydrogen bond)
Calcitonin salmon Y131 N-term hydrophobic
Calcitonin salmon L142 1.33x33 TM1 hydrophobic
Calcitonin salmon Y146 1.37x37 TM1 hydrophobic
Calcitonin salmon Y149 1.40x40 TM1 hydrophobic
Calcitonin salmon H201 2.67x67 TM2 polar (hydrogen bond)
Calcitonin salmon V206 ECL1 hydrophobic
Calcitonin salmon L291 45.52x52 ECL2 hydrophobic
Calcitonin salmon V293 ECL2 polar (hydrogen bond with backbone)
Calcitonin salmon V293 ECL2 polar (hydrogen bond with backbone)
Calcitonin salmon E294 ECL2 polar (charge-assisted hydrogen bond)
Calcitonin salmon E294 ECL2 polar (charge-assisted hydrogen bond)
Calcitonin salmon H302 5.40x40 TM5 polar (hydrogen bond)
Calcitonin salmon H302 5.40x40 TM5 polar (hydrogen bond)
Calcitonin salmon F356 6.53x53 TM6 hydrophobic
Calcitonin salmon P360 ECL3 polar (hydrogen bond with backbone)
Calcitonin salmon W361 ECL3 hydrophobic
Calcitonin salmon R362 ECL3 polar (hydrogen bond with backbone)

Ligands

Calcitonin salmon

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Residue Diagrams

V L T F I S L S H G V I A L Y Y L V Y A 1 K N M F L T Y I L N S M I I I I H L V E 2 C L M W F Y N C A M M Y Q H F F H L I K 3 R L R W Y Y L G L W G F P L V P T T I H A 4 L F F F N V V L A A M V P G H I I Y L 5 M I L V P L L G I Q F V V F P W 6 T A V F F G Q F H I L S H M V Y D Y I 7
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ICL1 R S L G ICL1ECL1 V P N G E L V R R D ECL1ICL2 A V F T E K Q ICL2ECL2 N D N C W L S V E T H L ECL2ICL3 E ICL3ECL3 R P S ECL3N-term M R F T F T S R C L A L F L L L N H P T P I L P A F S N Q T Y P T I E P K P F L Y V V G R K K M M D A Q Y K C Y D R M Q Q L P A Y Q G E G P Y C N R T W D G W L C W D D T P A G V L S Y Q F C P D Y F P D F D P S E K V T K Y C D E K G V W F K H P E N N R T W S N Y N-termC-term P S N R S A R A A A A A A E A G D I P I Y I C H Q E P R N E P A N N Q G E E S A E I I P L N I I E Q E S S A C-term T M C N A F T P E K L K N A Y V L Y Y L A I V G H S L S I F T L V I S L G I F V F F C Q R V T L H K N M F L T Y I L N S M I I I I H L V E V P V S C K I L H F F H Q Y M M A C N Y F W M L C E G I Y L H T L I V V R L R W Y Y L L G W G F P L V P T T I H A I T R A V Y F L Y I I H G P V M A A L V V N F F F L L N I V R V L V T K M R E T H A E S H M Y L K A V K A T M I L V P L L G I Q F V V F P W N K M L G K I Y D Y V M H S L I H F Q G F F V A T I Y C F C N N E V K R F K I R W G V Q T T Q W A Q Q W N Q R R
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Residue Table


GPCRdb(A)
GPCRdb(B)
CT receptor
TM1
1x29 1.33x33 L142
1x33 1.37x37 Y146
1x36 1.40x40 Y149
TM2
2x60 2.67x67 H201
ECL2
45x52 45.52x52 L291
TM5
5x44 5.40x40 H302
TM6
6x48 6.53x53 F356