Structure information

ADGRF1

PROTEIN CLASS

Class B2 (Adhesion)

PDB CODE

8G2Y

SPECIES

Homo sapiens

RESOLUTION

3.440

PREFERRED CHAIN

R

REFERENCE

10.1038/S41467-023-38083-7

PUBLICATION DATE

May 10, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
[1-Myristoyl-glycerol-3-YL]phosphonylcholine I625 2.48x48 TM2 hydrophobic
[1-Myristoyl-glycerol-3-YL]phosphonylcholine M677 3.49x49 TM3 hydrophobic
[1-Myristoyl-glycerol-3-YL]phosphonylcholine I680 3.52x52 TM3 polar (hydrogen bond)
[1-Myristoyl-glycerol-3-YL]phosphonylcholine L681 3.53x53 TM3 Van der Waals
[1-Myristoyl-glycerol-3-YL]phosphonylcholine L681 3.53x53 TM3 hydrophobic
[1-Myristoyl-glycerol-3-YL]phosphonylcholine Y684 3.56x56 TM3 Van der Waals
[1-Myristoyl-glycerol-3-YL]phosphonylcholine Y684 3.56x56 TM3 hydrophobic
[1-Myristoyl-glycerol-3-YL]phosphonylcholine L688 3.60x60 TM3 Van der Waals
[1-Myristoyl-glycerol-3-YL]phosphonylcholine M698 4.41x42 TM4 hydrophobic
[1-Myristoyl-glycerol-3-YL]phosphonylcholine M698 4.41x42 TM4 Van der Waals
[1-Myristoyl-glycerol-3-YL]phosphonylcholine M699 4.42x43 TM4 Van der Waals
[1-Myristoyl-glycerol-3-YL]phosphonylcholine V701 4.44x45 TM4 polar (hydrogen bond)
[1-Myristoyl-glycerol-3-YL]phosphonylcholine G702 4.45x46 TM4 Van der Waals
[1-Myristoyl-glycerol-3-YL]phosphonylcholine L705 4.48x49 TM4 Van der Waals

Ligands

[1-Myristoyl-glycerol-3-YL]phosphonylcholine

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Residue Diagrams

I L S G I S I G L G V Y T I W K V V P F 1 V N I A L S L L I A D V W F I V G A T V 2 M L M W F F L S L Y F F H T F F V A A T 3 M M A V G F C G L Y G C P L I I S V I T I 4 V V V F N V A V I A L A P V V F A L L P 5 L I L T P L L G L T W G F G I G T I V D 6 C L I F F G Q F A N L L A F I V H W A 7
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ICL1 K Q I K K ICL1ECL1 D T T V N P ECL1ICL2 V F H H M ICL2ECL2 P S N T Y K R K D V C W L N W S N G S ECL2ICL3 P T V G E R L S R ICL3ECL3 Q ECL3N-term M K V G V L W L I S F F T F T D G H G G F L G K N D G I K T K K E L I V N K K K H L G P V E E Y Q L L L Q V T Y R D S K E K R D L R N F L K L L K P P L L W S H G L I R I I R A K A T T D C N S L N G V L Q C T C E D S Y T W F P P S C L D P Q N C Y L H T A G A L P S C E C H L N N L S Q S V N F C E R T K I W G T F K I N E R F T N D L L N S S S A I Y S K Y A N G I E I Q L K K A Y E R I Q G F E S V Q V T Q F R N G S I V A G Y E V V G S S S A S E L L S A I E H V A E K A K T A L H K L F P L E D G S F R V F G K A Q C N D I V F G F G S K D D E Y T L P C S S G Y R G N I T A K C E S S G W Q V I R E T C V L N-termC-term W K Q T E K Q N S S D L S A K P K F S K P F N P L Q N K G H Y A F S H T G D S S D N I M L T Q F V S N E C-term P S T I F P V V K W I T Y V G L G I S I G S L I L C L I I E A L F W S Q T S H T R R I C M V N I A L S L L I A D V W F I V G A T V S G V C T A A V F F T H F F Y L S L F F W M L M L G I L L A Y R I I L A Q H L M M A V G F C L G Y G C P L I I S V I T I A V T Q K P L L A F V V P A L A I V A V N F V V V L L V L T K L W R D D K A T I I R V G K S L L I L T P L L G L T W G F G I G T I V D S N L A W H V I F A L L N A F Q G F F I L C F G I L L D S K L F N L S S L R Q L K L S A
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Residue Table


GPCRdb(A)
GPCRdb(B)
ADGRF1
TM2
2x41 2.48x48 I625
TM3
3x45 3.49x49 M677
3x48 3.52x52 I680
3x49 3.53x53 L681
3x52 3.56x56 Y684
3x56 3.60x60 L688
TM4
4x42 4.41x42 M698
4x43 4.42x43 M699
4x45 4.44x45 V701
4x46 4.45x46 G702
4x49 4.48x49 L705