Structure information

mGlu3 receptor

PROTEIN CLASS

Class C (Glutamate)

PDB CODE

8TR2

SPECIES

Homo sapiens

RESOLUTION

3.500

PREFERRED CHAIN

A

REFERENCE

10.1101/2023.08.13.552748

PUBLICATION DATE

July 31, 2024
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid R64 N-term polar (charge-assisted hydrogen bond)
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid R68 N-term polar (charge-assisted hydrogen bond)
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid S149 N-term polar (hydrogen bond with backbone)
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid S149 N-term Van der Waals
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid Y150 N-term Van der Waals
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid S151 N-term polar (hydrogen bond with backbone)
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid S151 N-term Van der Waals
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid A172 N-term Van der Waals
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid S173 N-term Van der Waals
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid T174 N-term polar (hydrogen bond with backbone)
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid T174 N-term polar (hydrogen bond)
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid T174 N-term Van der Waals
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid Y222 N-term hydrophobic
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid Y222 N-term Van der Waals
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid D301 N-term polar (charge-assisted hydrogen bond)
(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid K389 N-term polar (charge-assisted hydrogen bond)
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 16 of 16 entries

Ligands

(1S,4R,5R,6S)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid

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Residue Diagrams

C T C M F G L C A I T V P G I A W 1 Y I L L F G V G L S Y C M T F F F I 2 T L L A S Y C I A F S S G L G L R R L A 3 Q V F I C L G L I L V Q I V M V S V W L 4 A Y V T C L I V L I V D Y T L S I L M S 5 G F T M Y T T C I I W L A F L P I F Y V 6 G L V V F G S L S V S I C M T T T Q V R 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term W A I G P V T I A C L G F M C T C M V V T V F I K H G R E L C Y I L L F G V G L S Y C M T F F F I S P V I C A L R R L G L G S S F A I C Y S A L L T K T N C I A R I F S P S S Q V F I C L G L I L V Q I V M V S V W L I L E K D S S M L I S L T Y D V I L V I L C T V Y A F K T E A K F I G F T M Y T T C I I W L A F L P I F Y V T R V Q T T T M C I S V S L S G F V V L G C L F A P K V H I I L F Q P Q K H R L N V V T H L
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Residue Table


GPCRdb(A)
GPCRdb(C)
mGlu3 receptor