PDB
8XOF
Resolution
2.6 Å
Released
April 10, 2024
Receptor
GPER
Class
A
Species
Homo sapiens
Ligand
Function
Lys05
Agonist
Reference
—

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Lys05 L108 2.53x53 TM2 hydrophobic
Lys05 E115 2.60x60 TM2 Van der Waals
Lys05 L137 3.32x32 TM3 Van der Waals
Lys05 M141 3.36x36 TM3 Van der Waals
Lys05 W272 6.48x48 TM6 hydrophobic
Lys05 E275 6.51x51 TM6 polar (hydrogen bond)
Lys05 E275 6.51x51 TM6 polar (charge-charge)
Lys05 F278 6.54x54 TM6 aromatic (edge-to-face)
Lys05 H282 6.58x58 TM6 aromatic (edge-to-face)
Lys05 H282 6.58x58 TM6 hydrophobic
Lys05 H300 ECL3 Van der Waals
Lys05 A301 ECL3 Van der Waals
Lys05 N310 7.39x38 TM7 Van der Waals
Lys05 A313 7.42x41 TM7 hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 R E K M ICL1ECL1 Y Y D I ECL1ICL2 A M R C S L F R ICL2ECL2 T D E A C F C F A D ECL2ICL3 H R G L R P R ICL3ECL3 P G A A P C ECL3N-term M D V T S Q A R G V G L E M Y P G T A Q P A A P N T T S P E L N L S H P L L G T A L A N G T G E L S N-termC-term T N L P A L N R F C H A A L K A V I P D S T E Q S D V R F S S A V C-term E H Q Q Y V I G L F L S C L Y T I F L F P I G F V G N I L I L V V N I S F T I P D L Y F I N L A V A D L I L V A D S L I E V F N L H E R A V L C T F M S L F L Q V N M Y S S V F F L T W M S F D R Y I A L A R T K H H A R L S C G L I W M A S V S A T L V P F T A V H L Q H V R E V Q W L E V T L G F I V P F A I I G L C Y S L I V R V L V R A H R R Q K A L R M I L A V V L V F F V C W L P E N V F I S V H L L Q R T Q K Q S F R H A H P L T G H I V N L A A F S N S C L N P L I Y S F L G E T L R L K F R D K Y I E Q
Helix box plot — Download: PNG | SVG I N G V F G I P F L F I T Y L C S L F L 1 I N L A V A D L I L V A D S L I E V F N 2 W T L F F V S S Y M N V Q L F L S M F T 3 A R L S C G L I W M A S V S A T L V P F 4 Y C L G I I A F P V I F G L T V E L W Q V 5 L A V V L V F F V C W L P E N V F I S V 6 L P N L C S N S F A A L N V I H G T L 7

GPCRdb(A)
GPCRdb(A)
GPER
TM2
2x53 2.53x53 L108
2x60 2.60x60 E115
TM3
3x32 3.32x32 L137
3x36 3.36x36 M141
TM6
6x48 6.48x48 W272
6x51 6.51x51 E275
6x54 6.54x54 F278
6x58 6.58x58 H282
TM7
7x38 7.39x38 N310
7x41 7.42x41 A313