flesinoxan


SMILES OC[C@H]1COc2c(O1)cccc2N1CCN(CC1)CCNC(=O)c1ccc(cc1)F
InChIKey NYSDRDDQELAVKP-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 415.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A3 AA3R Rat Adenosine A pKi 5.51 5.51 5.51 PDSP Ki database
A2A AA2AR Rat Adenosine A pKi 6.48 6.48 6.48 PDSP Ki database
A2A AA2AR Human Adenosine A pKi 5.0 5.0 5.0 PDSP Ki database
A3 AA3R Human Adenosine A pKi 5.0 5.0 5.0 PDSP Ki database
PAF PTAFR Human Platelet-activating factor A pKi 6.89 7.76 8.85 PDSP Ki database
TP TA2R Human Prostanoid A pKd 7.0 7.0 7.0 Guide to Pharmacology
A1 AA1R Human Adenosine A pKi 5.0 5.0 5.0 PDSP Ki database
A1 AA1R Rat Adenosine A pKi 6.61 6.61 6.61 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database