17β-estradiol


SMILES Oc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2O)C
InChIKey VOXZDWNPVJITMN-ZBRFXRBCSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 272.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Endogenous
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT2 AGTR2 Human Angiotensin A pKi 9.4 9.4 9.4 Guide to Pharmacology
AT2 AGTR2 Human Angiotensin A pKi 8.01 9.02 9.4 ChEMBL
AT1 AGTR1 Human Angiotensin A pKi 5.0 5.0 5.0 ChEMBL
AT1 AGTR1 Pig Angiotensin A pKi 9.4 9.4 9.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT2 AGTR2 Human Angiotensin A pEC50 4.8 4.8 4.8 Guide to Pharmacology
AT2 AGTR2 Rat Angiotensin A pEC50 5.6 5.7 5.8 Guide to Pharmacology