NFP


SMILES Oc1ccc2c3c1O[C@@H]1C43CCN([C@H](C2)[C@]4(O)CC[C@H]1NC(=O)c1ccncc1F)CC1CC1
InChIKey JRUPWWCGTBJDNY-LNMFUWNLSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 465.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.8 6.8 6.8 Guide to Pharmacology
κ OPRK Human Opioid A pKi 8.32 8.32 8.32 Guide to Pharmacology
μ OPRM Human Opioid A pKi 9.44 9.44 9.44 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database