SANT-2


SMILES CCOc1c(OCC)cc(cc1OCC)C(=O)Nc1ccc(c(c1)c1nc2c([nH]1)cccc2)Cl
InChIKey VQOJFGFKIVFMDH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 479.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 6.29 6.29 6.29 ChEMBL
δ OPRD Human Opioid A pKi 5.59 5.59 5.59 ChEMBL
κ OPRK Human Opioid A pKi 5.64 5.64 5.64 ChEMBL
μ OPRM Human Opioid A pKi 6.0 6.0 6.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database