rosiglitazone


SMILES O=C1NC(=O)C(S1)Cc1ccc(cc1)OCCN(c1ccccn1)C
InChIKey YASAKCUCGLMORW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 357.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OT OXYR Human Vasopressin and oxytocin A pKi 8.9 8.9 8.9 Guide to Pharmacology
V1A V1AR Human Vasopressin and oxytocin A pKi 5.2 5.2 5.2 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pKi 6.2 6.2 6.2 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pKi 8.9 8.9 8.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database