rosiglitazone
SMILES | O=C1NC(=O)C(S1)Cc1ccc(cc1)OCCN(c1ccccn1)C |
InChIKey | YASAKCUCGLMORW-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 6 |
Hydrogen bond donors | 1 |
Rotatable bonds | 7 |
Molecular weight (Da) | 357.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | Yes |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
AT1 | AGTRA | Rat | Angiotensin | A | pKi | 9.64 | 9.64 | 9.64 | ChEMBL |
AT1 | AGTRA | Rat | Angiotensin | A | pKi | 8.02 | 8.02 | 8.02 | Drug Central |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
FFA1 | FFAR1 | Human | Free fatty acid | A | pEC50 | 4.94 | 4.94 | 4.94 | ChEMBL |
FFA1 | FFAR1 | Human | Free fatty acid | A | pEC50 | 8.25 | 8.25 | 8.25 | Drug Central |
FFA1 | FFAR1 | Human | Free fatty acid | A | pEC50 | 5.6 | 5.6 | 5.6 | Guide to Pharmacology |