CGP 56999A


SMILES O[C@H](CP(=O)(CC1CCCCC1)O)CN[C@@H](c1cccc(c1)C(=O)O)C
InChIKey JCFULPDIJOVUHP-KDOFPFPSSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 9
Molecular weight (Da) 383.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.22 6.22 6.22 Guide to Pharmacology
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.22 6.22 6.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 5.82 5.82 5.82 Guide to Pharmacology
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 5.1 5.1 5.1 Guide to Pharmacology
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 5.05 5.05 5.05 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pIC50 5.82 5.82 5.82 ChEMBL