UR-PG131A


SMILES O=C(CC(c1ccc(c(c1)F)F)c1ncc[nH]1)NC(=NCCCc1cnc[nH]1)N
InChIKey DGJMWXIXZSWRLP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 8
Molecular weight (Da) 401.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR6 GPR6 Human A orphans A pKi 8.03 8.14 8.26 ChEMBL
GPR6 GPR6 Human A orphans A pKi 8.03 8.03 8.03 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR6 GPR6 Human A orphans A pEC50 4.42 5.81 7.2 ChEMBL