FUB 349


SMILES c1ccc(cc1)CCCCc1cnc[nH]1
InChIKey BQTXNCXSCSNHGA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 200.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SMO SMO Human Frizzled F pKi 6.63 7.27 7.9 ChEMBL
SMO SMO Human Frizzled F pKd 6.94 7.43 7.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SMO SMO Mouse Frizzled F pIC50 5.72 5.95 6.32 ChEMBL
SMO SMO Human Frizzled F pIC50 6.52 6.75 7.19 ChEMBL
SMO SMO Mouse Frizzled F pIC50 7.0 7.0 7.0 Guide to Pharmacology