DCG-IV


SMILES N[C@@H](C1[C@H]([C@@H]1C(=O)O)C(=O)O)C(=O)O
InChIKey MATPZHBYOVDBLI-JJYYJPOSSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 203.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 7.6 8.6 9.6 Guide to Pharmacology
α2B ADA2B Human Adrenoceptors A pKi 7.5 8.6 9.7 Guide to Pharmacology
α2C ADA2C Human Adrenoceptors A pKi 7.0 8.15 9.3 Guide to Pharmacology
α2A ADA2A Rat Adrenoceptors A pKi 8.3 9.98 10.82 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.51 7.51 7.51 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 10.82 10.82 10.82 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.6 8.6 8.6 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.17 8.17 8.17 Drug Central
α1B ADA1B Human Adrenoceptors A pKi 8.19 8.19 8.19 Drug Central
α1D ADA1D Human Adrenoceptors A pKi 7.97 7.97 7.97 Drug Central
α2B ADA2B Human Adrenoceptors A pKi 8.01 8.01 8.01 Drug Central
α2C ADA2C Human Adrenoceptors A pKi 8.03 8.03 8.03 Drug Central
α2A ADA2A Rat Adrenoceptors A pKi 7.97 7.97 7.97 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Bovine Adrenoceptors A pEC50 6.42 6.42 6.42 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 9.32 9.32 9.32 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 8.67 8.86 9.1 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 8.05 8.05 8.05 Drug Central
α1A ADA1A Bovine Adrenoceptors A pEC50 8.19 8.19 8.19 Drug Central
TSH TSHR Human Glycoprotein hormone A Potency 4.5 4.5 4.5 ChEMBL