ACPT-I


SMILES OC(=O)[C@@H]1C[C@](C[C@@H]1C(=O)O)(N)C(=O)O
InChIKey FERIKTBTNCSGJS-KIGHRTHISA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 3
Molecular weight (Da) 217.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 9.3 9.3 9.3 Guide to Pharmacology
κ OPRK Human Opioid A pKi 9.6 9.65 9.7 Guide to Pharmacology
μ OPRM Human Opioid A pKi 9.1 9.1 9.1 Guide to Pharmacology
μ OPRM Mouse Opioid A pKi 10.1 10.1 10.1 Guide to Pharmacology
κ OPRK Human Opioid A pKd 10.54 10.54 10.54 ChEMBL
κ OPRK Human Opioid A pKi 9.16 9.65 10.7 ChEMBL
μ OPRM Human Opioid A pKi 9.48 9.76 10.15 ChEMBL
μ OPRM Human Opioid A pKi 9.1 9.64 10.15 PDSP Ki database
δ OPRD Human Opioid A pKi 9.23 9.39 9.64 PDSP Ki database
κ OPRK Human Opioid A pKi 9.7 10.35 11.0 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 9.4 9.4 9.4 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 9.52 9.52 9.52 PDSP Ki database
μ OPRM Mouse Opioid A pKi 9.92 10.22 10.52 PDSP Ki database
μ OPRM Rat Opioid A pKi 5.0 7.87 9.3 PDSP Ki database
κ OPRK Rat Opioid A pKi 5.0 5.0 5.0 PDSP Ki database
δ OPRD Human Opioid A pKi 9.64 9.64 9.64 ChEMBL
κ OPRK Rat Opioid A pKd 10.3 10.39 10.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Bovine Opioid A pIC50 8.85 8.85 8.85 ChEMBL
δ OPRD Human Opioid A pIC50 9.17 9.17 9.17 ChEMBL
κ OPRK Guinea pig Opioid A pIC50 8.74 8.74 8.74 ChEMBL