fenobam


SMILES O=C(NC1=NC(=O)CN1C)Nc1cccc(c1)Cl
InChIKey DWPQODZAOSWNHB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 266.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 6FFH
Ligand site mutations mGlu5

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TP TA2R Mouse Prostanoid A pKi 9.2 9.2 9.2 Guide to Pharmacology
TP TA2R Mouse Prostanoid A pKd 8.5 8.5 8.5 Guide to Pharmacology
TP TA2R Human Prostanoid A pKd 8.9 8.9 8.9 Guide to Pharmacology
TP TA2R Human Prostanoid A pKi 9.6 9.6 9.6 Guide to Pharmacology
TP TA2R Human Prostanoid A pKi 8.02 8.02 8.02 Drug Central
TP TA2R Mouse Prostanoid A pKi 8.04 8.04 8.04 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database