erythromycin


SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](C(=O)[C@@H]([C@H]([C@]1(C)O)O)C)C)(C)O
InChIKey ULGZDMOVFRHVEP-RWJQBGPGSA-N

Chemical properties

Hydrogen bond acceptors 14
Hydrogen bond donors 5
Rotatable bonds 7
Molecular weight (Da) 733.5

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 8IBU

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 Guide to Pharmacology
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.3 7.3 7.3 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.48 8.66 8.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.98 6.98 6.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database