(+)-DOI


SMILES COc1cc(I)c(cc1C[C@@H](N)C)OC
InChIKey BGMZUEKZENQUJY-ZETCQYMHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 321.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 5.7 5.7 5.7 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 6.7 6.7 6.7 Guide to Pharmacology
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 6.51 6.51 6.51 Guide to Pharmacology