(-)-bremazocine


SMILES CC[C@]12CCN([C@@H](C2(C)C)Cc2c1cc(O)cc2)CC1(O)CC1
InChIKey ZDXGFIXMPOUDFF-XLIONFOSSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 315.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 7.57 7.57 7.57 Guide to Pharmacology
H1 HRH1 Human Histamine A pKi 7.57 7.57 7.57 ChEMBL
H1 HRH1 Human Histamine A pKi 5.0 7.14 8.0 PDSP Ki database
H1 HRH1 Human Histamine A pKi 8.1 8.1 8.1 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pIC50 7.11 7.29 7.82 ChEMBL