quadazocine


SMILES O=C(CCC1(C)[C@H]2Cc3c([C@]1(C)CCN2C)cc(cc3)O)CCC1CCCC1
InChIKey LOYWOYCPSWPKFH-CSIQULDISA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 383.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Human Prostanoid A pKi 6.15 6.15 6.15 Guide to Pharmacology
FP PF2R Human Prostanoid A pKi 8.6 8.6 8.6 Guide to Pharmacology
TP TA2R Human Prostanoid A pKi 4.3 4.3 4.3 Guide to Pharmacology
FP PF2R Mouse Prostanoid A pKi 8.4 8.4 8.4 Guide to Pharmacology
FP PF2R Mouse Prostanoid A pKi 8.42 8.42 8.42 PDSP Ki database
EP3 PE2R3 Bovine Prostanoid A pKi 5.46 5.48 5.5 PDSP Ki database
FP PF2R Bovine Prostanoid A pKi 7.0 7.0 7.0 PDSP Ki database
EP1 PE2R1 Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
EP3 PE2R3 Human Prostanoid A pKi 6.15 6.15 6.15 PDSP Ki database
EP4 PE2R4 Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
DP1 PD2R Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
IP PI2R Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
FP PF2R Human Prostanoid A pKi 8.64 8.64 8.64 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FP PF2R Human Prostanoid A pEC50 8.44 8.44 8.44 ChEMBL
EP3 PE2R3 Human Prostanoid A pEC50 5.47 5.47 5.47 ChEMBL