diquafosol


SMILES O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@@H]([C@@H]2O)O)n2ccc(=O)[nH]c2=O)O)O)O)O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O
InChIKey NMLMACJWHPHKGR-NCOIDOBVSA-N

Chemical properties

Hydrogen bond acceptors 21
Hydrogen bond donors 10
Rotatable bonds 14
Molecular weight (Da) 790.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GIP GIPR Human Glucagon B1 pKd 8.7 8.7 8.7 Guide to Pharmacology
GIP GIPR Human Glucagon B1 pKi 9.12 9.12 9.12 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GIP GIPR Rat Glucagon B1 pIC50 8.6 8.6 8.6 Guide to Pharmacology