guanosine-5'-triphosphate


SMILES O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@@H]1O)n1cnc2c1[nH]c(N)nc2=O
InChIKey XKMLYUALXHKNFT-UUOKFMHZSA-N

Chemical properties

Hydrogen bond acceptors 14
Hydrogen bond donors 8
Rotatable bonds 8
Molecular weight (Da) 523.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 6.8 6.89 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Rat Cannabinoid A pEC50 6.62 7.54 7.77 ChEMBL
CB1 CNR1 Human Cannabinoid A pEC50 5.92 6.68 8.09 ChEMBL
CB1 CNR1 Mouse Cannabinoid A pEC50 6.03 6.03 6.03 ChEMBL