2-O-ethyl-PAF C-16


SMILES CCCCCCCCCCCCCCCCOCC(COP(=O)(OCC[N+](C)(C)C)O)OCC
InChIKey LPHUUVMLQFHHQG-UHFFFAOYSA-O

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 26
Molecular weight (Da) 510.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pKi 7.89 7.89 7.89 Guide to Pharmacology
EP4 Q9TU16 Dog Prostanoid A pKi 7.62 7.62 7.62 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKd 8.11 8.11 8.11 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 6.35 6.86 7.89 ChEMBL
EP4 PE2R4 Human Prostanoid A pKd 8.32 8.32 8.32 ChEMBL
EP4 PE2R4 Rat Prostanoid A pKd 8.19 8.19 8.19 ChEMBL
EP4 PE2R4 Rat Prostanoid A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pIC50 5.79 6.65 7.93 ChEMBL