PAF


SMILES CCCCCCCCCCCCCCCCOC[C@@H](OC(=O)C)COP(=O)(OCC[N+](C)(C)C)[O-]
InChIKey HVAUUPRFYPCOCA-AREMUKBSSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 25
Molecular weight (Da) 523.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Endogenous
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.2 6.2 6.2 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.3 5.3 5.3 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.3 5.3 5.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.1 7.1 7.1 Guide to Pharmacology
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 5.7 6.4 7.1 ChEMBL