SC-51322


SMILES O=C(NNC(=O)N1Cc2ccccc2Oc2c1cc(Cl)cc2)CCSCc1ccco1
InChIKey CQBVTZDISUKDSX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 457.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.42 7.42 7.42 Guide to Pharmacology
κ OPRK Human Opioid A pKi 8.55 8.55 8.55 Guide to Pharmacology
δ OPRD Human Opioid A pKi 7.42 7.42 7.42 ChEMBL
κ OPRK Human Opioid A pKi 8.55 8.55 8.55 ChEMBL
μ OPRM Human Opioid A pKi 9.55 9.55 9.55 ChEMBL
δ OPRD Human Opioid A pKi 8.13 8.13 8.13 Drug Central
κ OPRK Human Opioid A pKi 8.07 8.07 8.07 Drug Central
μ OPRM Human Opioid A pKi 8.02 8.02 8.02 Drug Central
μ OPRM Human Opioid A pKi 9.55 9.55 9.55 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pEC50 7.96 7.96 7.96 ChEMBL
μ OPRM Human Opioid A pEC50 8.59 8.59 8.59 ChEMBL