bimatoprost (free acid form)


SMILES OC(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@H]([C@@H]1/C=C/[C@H](CCc1ccccc1)O)O
InChIKey YFHHIZGZVLHBQZ-KDACTHKWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 11
Molecular weight (Da) 388.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT1 MTR1A Human Melatonin A pKi 8.3 8.3 8.3 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 10.3 10.3 10.3 Guide to Pharmacology
MT2 MTR1B Mouse Melatonin A pKi 10.3 10.3 10.3 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 10.3 10.3 10.3 ChEMBL
MT1 MTR1A Human Melatonin A pKi 8.35 8.35 8.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPS NPSR1 Human Neuropeptide S A Potency 5.0 5.0 5.0 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 5.1 5.1 5.1 ChEMBL