osanetant


SMILES O=C(N1CCC[C@](C1)(CCCN1CCC(CC1)(c1ccccc1)N(C(=O)C)C)c1ccc(c(c1)Cl)Cl)c1ccccc1
InChIKey DZOJBGLFWINFBF-UMSFTDKQSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 605.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
UT UR2R Human Urotensin A pKi 8.4 8.4 8.4 Guide to Pharmacology
UT UR2R Human Urotensin A pKi 8.4 8.4 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
UT UR2R Human Urotensin A pIC50 8.1 8.1 8.1 ChEMBL
UT UR2R Rat Urotensin A pIC50 9.0 9.0 9.0 ChEMBL