d(CH2)5[Tyr(Me)2,Thr4,Tyr-NH29]OVT


SMILES None
InChIKey None
Sequence CYITNCPXY

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.7 7.7 7.7 Guide to Pharmacology
α1B ADA1B Rat Adrenoceptors A pKi 8.3 8.3 8.3 Guide to Pharmacology
α1B ADA1B Rat Adrenoceptors A pKi 8.27 8.27 8.27 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 8.7 8.7 8.7 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.3 6.3 6.3 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.38 6.38 6.38 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.47 7.47 7.47 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKi 7.3 7.3 7.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Rat Adrenoceptors A pIC50 8.03 8.03 8.03 ChEMBL
α1B ADA1B Human Adrenoceptors A pIC50 5.24 6.65 8.06 ChEMBL
α1A ADA1A Rat Adrenoceptors A pIC50 6.47 6.47 6.47 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.7 4.7 4.7 ChEMBL
α1A ADA1A Human Adrenoceptors A pIC50 6.23 6.23 6.23 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 6.1 6.1 6.1 ChEMBL