d(CH2)5[Tyr(Me)2]AVP


SMILES None
InChIKey QVQOGNOOAMQKCE-OVSZNHMYSA-N
Sequence CYFQNCPRG

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.3 6.6 6.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Mouse 5-Hydroxytryptamine A pIC50 7.26 7.26 7.26 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 7.12 7.13 7.14 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pEC50 6.37 6.37 6.37 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 8.92 8.96 9.0 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 9.22 9.25 9.3 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.05 5.05 5.05 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.43 6.43 6.43 ChEMBL
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pIC50 5.42 5.42 5.42 ChEMBL