picrotoxinin


SMILES CC(=C)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]1([C@]3([C@@H]2OC(=O)[C@]23[C@@H](C1)O2)C)O
InChIKey PIMZUZSSNYHVCU-YKWPQBAZSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 292.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Rat Cholecystokinin A pKi 9.24 9.24 9.24 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK1 CCKAR Human Cholecystokinin A pIC50 8.3 8.3 8.3 Guide to Pharmacology
CCK1 CCKAR Rat Cholecystokinin A pIC50 9.7 9.7 9.7 Guide to Pharmacology
CCK1 CCKAR Human Cholecystokinin A pIC50 9.25 9.25 9.25 ChEMBL