strychnine


SMILES O=C1C[C@@H]2OCC=C3[C@H]4[C@@H]2[C@@H]2N1c1ccccc1[C@]12CCN([C@H]1C4)C3
InChIKey QMGVPVSNSZLJIA-FVWCLLPLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 334.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 7XP6

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FPR2/ALX FPR2 Human Formylpeptide A pKd 8.77 9.04 9.3 Guide to Pharmacology
FPR2/ALX FPRS1 Mouse Formylpeptide A pKd 8.82 8.82 8.82 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FPR2/ALX FPR2 Human Formylpeptide A pEC50 12.0 12.0 12.0 Guide to Pharmacology
GPR32 GPR32 Human A orphans A pEC50 9.7 9.7 9.7 Guide to Pharmacology
FPR2/ALX FPR2 Human Formylpeptide A pIC50 7.58 8.13 8.77 ChEMBL