LTB4


SMILES CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O
InChIKey VNYSSYRCGWBHLG-AMOLWHMGSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 14
Molecular weight (Da) 336.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 7VKT

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
BLT1 LT4R1 Human Leukotriene A pKi 8.54 9.29 9.92 ChEMBL
BLT1 LT4R1 Human Leukotriene A pKi 9.4 9.4 9.4 Guide to Pharmacology
BLT2 LT4R2 Human Leukotriene A pKd 7.64 7.64 7.64 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
BLT1 LT4R1 Human Leukotriene A pIC50 7.5 8.31 8.72 ChEMBL
BLT2 LT4R2 Human Leukotriene A pIC50 7.6 7.6 7.6 Guide to Pharmacology
BLT2 LT4R2 Human Leukotriene A pEC50 6.85 6.85 6.85 Guide to Pharmacology