nicardipine


SMILES COC(=O)C1=C(C)NC(=C(C1c1cccc(c1)[N+](=O)[O-])C(=O)OCCN(Cc1ccccc1)C)C
InChIKey ZBBHBTPTTSWHBA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 479.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
motilin MTLR Human Motilin A pKi 8.4 8.55 8.7 Guide to Pharmacology
motilin MTLR Human Motilin A pKd 10.0 10.0 10.0 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
motilin MTLR Human Motilin A pEC50 9.01 9.71 10.4 ChEMBL