SB 216641


SMILES COc1ccc(cc1OCCN(C)C)NC(=O)c1ccc(cc1)c1ccc(cc1C)c1noc(n1)C
InChIKey JRNUKVFYILMMLX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 486.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Rat Prostanoid A pKi 6.8 6.8 6.8 Guide to Pharmacology
EP4 PE2R4 Rat Prostanoid A pKi 7.5 7.5 7.5 Guide to Pharmacology
EP2 PE2R2 Human Prostanoid A pKi 5.9 5.9 5.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database