KRP 203-phosphate


SMILES OCC(COP(=O)(O)O)(CCc1ccc(cc1Cl)Sc1cccc(c1)Oc1ccccc1)N
InChIKey BZVUYJGCYLMFGX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 11
Molecular weight (Da) 509.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2B AA2BR Human Adenosine A pKi 9.3 9.3 9.3 Guide to Pharmacology
A2B AA2BR Human Adenosine A pKd 9.8 9.8 9.8 Guide to Pharmacology
A2B AA2BR Human Adenosine A pKi 9.3 9.34 9.4 ChEMBL
A2B AA2BR Human Adenosine A pKd 9.77 9.77 9.77 ChEMBL
A3 AA3R Human Adenosine A pKi 6.35 6.35 6.35 ChEMBL
A2A AA2AR Human Adenosine A pKi 6.48 6.48 6.48 ChEMBL
A1 AA1R Human Adenosine A pKi 6.35 7.07 7.43 ChEMBL
A1 AA1R Human Adenosine A pKi 7.43 7.43 7.43 PDSP Ki database
A2A AA2AR Human Adenosine A pKi 6.48 6.48 6.48 PDSP Ki database
A2B AA2BR Human Adenosine A pKi 9.39 9.39 9.39 PDSP Ki database
A3 AA3R Human Adenosine A pKi 6.35 6.35 6.35 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database