arecaidine propargyl ester


SMILES CN1CC(=CCC1)C(=O)OCC#C
InChIKey SPHRJZBOFYIKMC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 179.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 5.44 5.44 5.44 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 6.8 6.8 6.8 Guide to Pharmacology
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 6.5 6.5 6.5 Guide to Pharmacology
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 7.26 7.26 7.26 Guide to Pharmacology
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 6.7 6.73 6.8 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 6.77 7.01 7.26 ChEMBL