arecaidine propargyl ester


SMILES CN1CC(=CCC1)C(=O)OCC#C
InChIKey SPHRJZBOFYIKMC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 179.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.4 6.4 6.4 Guide to Pharmacology
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.7 5.7 5.7 Guide to Pharmacology
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.7 5.7 5.7 Guide to Pharmacology
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.9 5.9 5.9 Guide to Pharmacology
M1 ACM1 Fruit fly Acetylcholine (muscarinic) A pKi 5.28 5.31 5.35 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.01 6.01 6.01 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.91 5.91 5.91 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.06 7.06 7.06 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.07 6.07 6.07 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.03 6.03 6.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database