milameline


SMILES CO/N=C/C1=CCCN(C1)C
InChIKey YMMXHEYLRHNXAB-RMKNXTFCSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 154.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 4.8 4.8 4.8 Guide to Pharmacology
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.1 5.1 5.1 Guide to Pharmacology
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.5 5.5 5.5 Guide to Pharmacology
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.4 5.4 5.4 Guide to Pharmacology
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.5 5.5 5.5 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.25 5.25 5.25 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.0 6.0 6.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pEC50 7.68 7.68 7.68 ChEMBL