PF-514273


SMILES Clc1c(cccc1)n1nc2C(=O)N(CCOc2c1c1ccc(cc1)Cl)CC(C)(F)F
InChIKey FJMQJSUOOGOWBD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 451.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 9.0 9.04 9.09 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 9.0 9.04 9.09 PDSP Ki database
CB1 CNR1 Human Cannabinoid A pKi 9.09 9.09 9.09 Guide to Pharmacology
CB2 CNR2 Human Cannabinoid A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database