8-OH-DPAT
| SMILES | CCCN(C1CCc2c(C1)c(O)ccc2)CCC |
| InChIKey | ASXGJMSKWNBENU-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 2 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 5 |
| Molecular weight (Da) | 247.2 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu6 | GRM6 | Human | Metabotropic glutamate | C | pKi | 4.7 | 4.7 | 4.7 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu6 | GRM6 | Rat | Metabotropic glutamate | C | pEC50 | 4.7 | 4.7 | 4.7 | Guide to Pharmacology |
| mGlu6 | GRM6 | Rat | Metabotropic glutamate | C | pEC50 | 4.7 | 4.7 | 4.7 | ChEMBL |