FR260010
| SMILES | Cc1ncn(c1)c1cccc(c1)Nc1ncnc2c1CCc1c2cccc1 |
| InChIKey | LFKNMCJSJZOQJF-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 3 |
| Molecular weight (Da) | 353.2 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| RXFP4 | RL3R2 | Human | Relaxin family peptide | A | pKi | 8.88 | 8.88 | 8.88 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| RXFP3 | RL3R1 | Human | Relaxin family peptide | A | pIC50 | 9.3 | 9.3 | 9.3 | Guide to Pharmacology |
| RXFP4 | RL3R2 | Human | Relaxin family peptide | A | pEC50 | 8.94 | 8.94 | 8.94 | Guide to Pharmacology |
| RXFP4 | RL3R2 | Human | Relaxin family peptide | A | pIC50 | 10.5 | 10.5 | 10.5 | Guide to Pharmacology |