SB399885


SMILES COc1ccc(cc1N1CCNCC1)S(=O)(=O)Nc1cc(Cl)cc(c1OC)Cl
InChIKey ATKZKAYWARYLBW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 445.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Rat Cholecystokinin A pKi 9.12 9.12 9.12 ChEMBL
CCK2 GASR Human Cholecystokinin A pKi 9.55 9.55 9.55 ChEMBL
CCK2 GASR Rat Cholecystokinin A pKi 9.1 9.1 9.1 Guide to Pharmacology
CCK1 CCKAR Guinea pig Cholecystokinin A pKi 9.12 9.12 9.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Rat Cholecystokinin A pEC50 9.4 9.4 9.4 ChEMBL