3-quinuclidinyl-benzilate


SMILES O=C(C(c1ccccc1)(c1ccccc1)O)OC1CN2CCC1CC2
InChIKey HGMITUYOCPPQLE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 337.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 10.4 10.4 10.4 Guide to Pharmacology
M4 ACM4 Human Acetylcholine (muscarinic) A pKd 9.7 10.1 10.5 Guide to Pharmacology
M3 ACM3 Human Acetylcholine (muscarinic) A pKd 10.4 10.4 10.4 Guide to Pharmacology
M5 ACM5 Human Acetylcholine (muscarinic) A pKd 10.22 10.46 10.7 Guide to Pharmacology
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 10.52 10.54 10.57 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 10.43 10.45 10.47 PDSP Ki database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 10.19 10.28 10.37 PDSP Ki database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 10.06 10.08 10.1 PDSP Ki database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 10.36 10.41 10.46 PDSP Ki database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 10.29 10.29 10.29 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKd 10.6 10.7 10.8 Guide to Pharmacology
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 10.35 10.35 10.35 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 10.1 10.35 10.6 Guide to Pharmacology
M1 ACM1 Fruit fly Acetylcholine (muscarinic) A pKi 9.3 9.3 9.3 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 9.74 9.74 9.74 ChEMBL
D2 DRD2 Rat Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database