A412997


SMILES O=C(Nc1cccc(c1)C)CN1CCC(CC1)c1ccccn1
InChIKey JFCDMGGMCUKHST-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 309.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR2 CXCR2 Human Chemokine A pIC50 7.7 7.7 7.7 Guide to Pharmacology
CXCR2 CXCR2 Human Chemokine A pIC50 7.4 7.56 7.66 ChEMBL
CXCR1 CXCR1 Human Chemokine A pIC50 7.66 7.66 7.66 ChEMBL