MMPIP


SMILES COc1ccc(cc1)c1cc2onc(c2c(=O)n1C)c1ccncc1
InChIKey PDWYBOZNEVALOV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 333.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 9.2 9.21 9.22 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.8 7.8 7.8 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.3 8.8 9.3 Guide to Pharmacology
α1B ADA1B Human Adrenoceptors A pKi 7.8 7.8 7.8 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.8 7.8 7.8 Guide to Pharmacology
α1A ADA1A Rabbit Adrenoceptors A pKd 7.3 7.3 7.3 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 9.1 9.1 9.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database