GW848687X


SMILES Clc1ccc(c(c1)C1=C(CCC1)c1cccc(n1)C(=O)O)OCc1ccc(cc1F)F
InChIKey PFODPHDNBFSMOX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 441.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pKd 9.1 9.1 9.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pIC50 8.6 8.6 8.6 ChEMBL
EP1 PE2R1 Human Prostanoid A pIC50 8.6 8.6 8.6 Guide to Pharmacology