CBiPES


SMILES N#Cc1ccc(cc1)c1cccc(c1)N(S(=O)(=O)CC)Cc1cccnc1
InChIKey HDVYXILCBYGKGU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 377.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 7.89 7.89 7.9 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.6 6.6 6.6 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.5 5.5 5.5 Guide to Pharmacology
D3 DRD3 Human Dopamine A pKi 7.48 7.78 7.94 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.9 7.39 7.89 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database