(S)-TBPG


SMILES OC(=O)[C@H](C12CC(C1)(C2)c1n[nH]nn1)N
InChIKey XYCORZCGVTXZFU-XOJFDHPMSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 209.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK2 NK2R Golden hamster Tachykinin A pKi 8.92 8.92 8.92 ChEMBL
NK2 NK2R Rat Tachykinin A pKi 6.03 7.67 9.3 ChEMBL
NK2 NK2R Human Tachykinin A pKi 9.3 9.3 9.3 ChEMBL
NK1 NK1R Human Tachykinin A pKi 6.1 6.35 6.6 Guide to Pharmacology
NK2 NK2R Human Tachykinin A pKi 9.4 9.55 9.7 Guide to Pharmacology
NK3 NK3R Human Tachykinin A pKi 5.7 5.95 6.2 Guide to Pharmacology
NK2 NK2R Rat Tachykinin A pKd 9.7 9.7 9.7 Guide to Pharmacology
NK2 NK2R Rat Tachykinin A pKi 9.2 9.3 9.4 Guide to Pharmacology
NK2 NK2R Bovine Tachykinin A pKi 9.3 9.3 9.3 ChEMBL
NK1 NK1R Rat Tachykinin A pKi 9.29 9.29 9.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NK3 NK3R Guinea pig Tachykinin A pIC50 6.68 6.68 6.68 ChEMBL
NK2 NK2R Human Tachykinin A pIC50 9.1 9.45 9.89 ChEMBL
NK1 NK1R Human Tachykinin A pIC50 6.1 6.17 6.23 ChEMBL
NK3 NK3R Human Tachykinin A pIC50 6.5 6.5 6.5 Guide to Pharmacology
NK2 NK2R Guinea pig Tachykinin A pIC50 10.25 10.25 10.25 Guide to Pharmacology